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KMID : 0378119810080020363
Chungnam Medical Journal
1981 Volume.8 No. 2 p.363 ~ p.371
A Study on Trend of Tuberculin Reaction following BCG Vaccination


Abstract
A author performed tuberculin tests following B. C. G. vaccination to 121 children under 5 years of age during the period of 6 months from Aug. 1980 to Jan. 1981 in order to clarify the time converted from negative to positive reaction following vaccination and compare two dried vaccines made in Korea and Japan on its effect on tuberculin test and side reaction.
The results were as follows :
1. Positive rate of Mantoux test before BCG Vaccination was 4. 9% and peaked at 3 to 4 years.
2. Abnormal chest P-A of positive tuberculin test prior to BCG vaccination was 66.6% and pulmonary tuberculosis was 3. 3% of total cases.
3. Positive conversion rate of tuberculin reaction after BCG vaccination peaked at 29. 1% in 6 weeks and total positive conversion rate was 86. 4%. Positive conversion reaction was usually detected from 2 weeks to 10 weeks.
4. Positive tuberculin rate became higher with age.
5. Positive BCG induration after BCG vaccination peaked at 30.9% in 4 weeks and general positive BCG rate was 83. 6% of total cases. Positive BCG rate was higher than positive tuberculin reaction until 4 weeks and lower than thereafter
6. The degrees of reaction between BCG and tuberculin tests were well proportional.
7. Positive conversion rate of Korean BCG vaccination was higher than that of Japan BCG vaccination, and their side reactions were similar in two groups.
8. Side reaction of BCG vaccination was encountered in 6.3% of total cases.
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